Using mouse-inducible melanoma models in which the expression of BRAFV600E was induced and Pten inactivated selectively in melanocytes by tamoxifen administration (BRAF/PTEN mice), Yao et al. [235] observed that TSLP expression increases in the epidermis overlying melanomas concomitantly with tumorigenesis. The gene discussed is TSLP; the disease is melanoma.