AKT1 and skin basal cell carcinoma: Additional events, including driver mutations in other cancer-related genes such as members of the Hippo-YAP, MYCN/FBXW7, EGFR, phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) pathways, and members of the protein kinase C (PKC) family, were also found in BCCs and contribute to BCC tumorigenesis and phenotypic diversity [61,67].