AKT1 and proximal spinal muscular atrophy: The dysregulation of the putative regulator of PI3K/AKT pathway hsa-miR-663a [115] reinforces the notion that alterations in PI3K/AKT pathway are a common feature in SMA and that the classic interplay between PI3K/AKT-FoxO-B-catenin found in atrophy, might be of capital relevance in SMA.