PDX1 and diabetes mellitus: In particular, some variants such as PDX1 (Pancreatic Duodenal Homeobox 1) variant P33T, E224, P242L (MODY4), HNF4A V169I (MODY1), BLK A71T (MODY11), and NEUROD1 (Neurogenic Differentiation 1) H241Q (MODY6) were reported in the study of Mohan et al. to have almost no impact in diabetes development.