The fluctuation of Hsp90β in the presence of GDM and RIT followed a behavior similar to that observed when complexed with ATP; that is, only the region between AA 200 and 300 showed high fluctuation with an RMSF as large as 15 Å ± 1.77 for GDM and ± 2.12 RIT, whereas the RMSF of the NTD and CD regions did not exceed 5 Å (Figure 6D and Figure S6). This evidence concerns the gene HSP90AB1 and gestational diabetes.