Indeed, both OCTN1 and OCTN2 genes are directly or indirectly linked with inflammatory diseases and cancer [14,16,17,18,19], and OCTN2 may be considered a “gene-disease” since several single nucleotide polymorphisms (SNPs) and mutations of this gene are causative of systemic primary carnitine deficiency (CDSP). Here, SLC22A5 is linked to systemic primary carnitine deficiency disease.