Furthermore, in the group of women with PCOS, increased concentrations of dehydroepiandrosterone sulfate (DHEA-S), total testosterone (tTest), and free testosterone (fTest) and increased values of the free androgen index (FAI) were detected, while the concentrations of high-density lipoprotein (HDL-C) and sex hormone-binding globulin (SHBG) were decreased. The gene discussed is SHBG; the disease is polycystic ovary syndrome.