Astaxanthin supplementation in the diet has positive effects for the modification of the symptoms associated with obesity in animals: a significant decrease in the weight of adipose tissue was found, systolic pressure was reduced, insulin sensitivity was improved, glycemia was reduced, as well as the levels of cholesterol, triacylglycerols (TAG), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) in the liver [53]. This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.