Although the mTOR pathway has been implicated in the development of diseases where alterations in the microbiome have been shown to play a crucial role, such as the progression of kidney injury in diabetic nephropathy [122], myocardial injury [123], dermatitis [124], and metabolic disease [125], the direct association between alterations in gut microbiota and mTOR remains unclear. The gene discussed is MTOR; the disease is diabetic kidney disease.