But IL1RAP (p = 4.234 × 10−11), CXCL3 (p = 0), CXCL5 (p = 0), and CXCL6 (p = 0) gene expression levels had higher expression in ER-negative than ER-positive ones; whereas IL6ST was the only gene whose expression was higher in ER-positive cancer patients (p = 0). This evidence concerns the gene IL6ST and cancer.