Figure 3 shows there was a significant (Spearman test, p < 0.05) positive correlation between IL1R1, IL1RN, and ESR1 gene expression in Basal patients; however, there was no significant difference in IL1RAP correlation in any subtype of breast cancer patients, but all were positive when the correlation was made between IL6ST and ESR1 gene expression in all breast cancer subtypes such as Basal, Her2, Luminal A, and Luminal B. The gene discussed is ERBB2; the disease is breast cancer.