In IELs, the frequencies of CD11b+ and CD11b+Ly6G+ cells in colitis mice were significantly higher than those in normal controls (p < 0.01) (Figure 7G,I), and CD11b+, Ly6G+, and CD11b+Ly6G+ cell frequencies were significantly downregulated in colitis mice after treatment with the probiotic mixture (Figure 7G–I). Here, ITGAM is linked to colitis.