NPPB and pulmonary arterial hypertension: In our cohort, we found that an early remission of NT-proBNP within 3 months from baseline could improve the prognosis, while a delayed remission of NT-proBNP after 6 or 9 months from baseline could not, which demonstrated the key role of the time to achieve NT-proBNP remission in the CTD-PAH prognosis prediction.