CSF3 and obesity due to melanocortin 4 receptor deficiency: Notably, among the ophthalmological variables, IL-5, G-CSF, and CCL11/eotaxin-1 concentrations were newly identified as tear inflammatory mediators predictive of the coexistence of T2DM after controlling for other prevalent cardiovascular risk factors (i.e., hypertension, hypercholesterolemia, obesity, smoking, sex, and age).