The construction of a logistic regression model with these tear cytokines to distinguish patients with CAD and comorbid T2DM from those without T2DM revealed IL-5, G-CSF, and CCL11/eotaxin-1 concentrations as promising inflammatory biomarkers associated with comorbid T2DM in the tear fluid of these patients. This evidence concerns the gene IL5 and type 2 diabetes mellitus.