Serum procalcitonin, a polypeptide produced by multiple tissues in the body, is not detectable in healthy individuals but is elevated in response to proinflammatory cytokines, such as interleukin-1, interleukin-6, tumor necrosis factor-α, etc. Serum procalcitonin has been used as a biomarker for sepsis, but it may also be elevated in response to severe bacterial infection [7,8,9,10]. This evidence concerns the gene TNF and Sepsis.