CFTR and familial pancreatic carcinoma: A case–control study by McWilliams et al. has also shown higher odds of developing pancreatic cancer in patients with a CFTR gene mutation as compared to controls (OR 1.40, 95% CI: 1.04–1.89), with a higher carrier frequency in younger (<60 years) individuals (OR 1.82, 95% CI: 1.14–2.94) [61].