Hereditary breast and ovarian cancer is an autosomal dominant disorder characterized by the mutation of BRCA1 and BRCA2 genes, which leads to an increased risk of breast cancer, ovarian cancer, and to a lesser extent, prostate cancer, pancreatic cancer, and melanoma, especially in patients with a BRCA2 mutation [27]. The gene discussed is BRCA2; the disease is pancreatic neoplasm.