A multi-center cohort study of 2227 individuals of 130 pancreatic cancer kindreds by Hsu et al. found that the risk of pancreatic cancer in patients with a pathogenic variation of the ATM gene is 1.1% by age 50 years, 6.3% by age 70 years, and 9.5% by age 80 years [54]. Here, ATM is linked to familial pancreatic carcinoma.