MAPT and Alzheimer disease: The dysregulation of miRNA, small ncRNAs of 20–22 nucleotides in length, which regulate the half gene expression post-transcriptionally by binding to the 3′ untranslated region (UTR) of target mRNAs, is implicated in various neurodegenerative disorders, including AD, where miRNAs can modulate the expression of genes involved in amyloid-beta metabolism, tau phosphorylation, neuroinflammation, and synaptic dysfunction [103].