The overweight or obese group also showed significantly higher levels of lipid profile indicators (total cholesterol, triglycerides, and LDL-cholesterol), except for HDL-cholesterol, as well as abnormal hyperglycemia markers such as FPG, HbA1C, insulin, and the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) compared to the healthy group. The gene discussed is INS; the disease is Insulin resistance.