Additionally, Planococcaceae influence blood sugar levels by modulating valine production; Bacteroides acidifaciens, a probiotic with anti-obesity effects, enhances IgA production, thereby improving gut immune function [42,43]; Gastranaerophilales represents a beneficial gut bacterium [44]; and Clostridia_UCG-014, a probiotic associated with tryptophan metabolism, regulates gut homeostasis [45]. The gene discussed is CD79A; the disease is obesity due to melanocortin 4 receptor deficiency.