In contrast to the first phase of pleural effusions around day 30, there were also relevant increases in NT-proBNP, CK, CRP (Figure 5c,d) as well as several chemokines and pro-inflammatory cytokines, like MCP-1, I-TAC, MIG, IL-6, IL-12, TNF-α and eotaxin (Figure 6). Here, NPPB is linked to Pleural effusion.