As regarded, previously in adrenal fat of patients with adrenal adenoma cortisol-secreting, we found higher expression of leptin mRNA levels and reduced adiponectin mRNA expression, both strictly related to plasma levels of both of them, suggesting a molecular mechanism favouring dyslipidemia, hyperglycemia, metabolic syndrome and adiposopathy [42]. This evidence concerns the gene ADIPOQ and Hyperglycemia.