Given the expected role of the KATP and BK channels in glioblastomas, we also investigated the antiproliferative effects of zoledronic acid, a recently identified KATP channel blocker targeting either the Kir6.1/2 and SUR2 subunits in native cells [43,44] and in cell lines transfected with KATP channel subunits [45]. Here, KCNMA1 is linked to glioblastoma.