Once more, although the clinical diagnosis suggested FTD, i.e., in this case, a behavioral variant, the genetic study intriguingly revealed a heterozygous deletion of two nucleotides at the acceptor splice site of the intron 11 of the PSEN2 gene NM_000447.3:c.1073-2_1073-1del, presumably resulting in exon 12 skipping during gene processing (Figure 2). The gene discussed is PSEN2; the disease is frontotemporal dementia.