ALB and Cushing syndrome due to macronodular adrenal hyperplasia: The increase in albuminuria in Cushing’s syndrome can be explained by abnormal lipid metabolism because GC increases visceral fat content, which leads to the increase in plasma-free fatty acid, finally binding to serum albumin and increasing the urinary albumin excretion or activating the protein kinase-C pathway in kidney endothelial cells [85].