However, the patients from the kidney-related event group were older, frequently had CAD, exhibited a higher serum creatinine and urinary albumin/creatinine ratio, and lower GLS, eGFR, and irisin levels, as well as being frequently treated with beta-blockers and rarely SGLT-2 inhibitors compared with those from another group. The gene discussed is SLC5A2; the disease is coronary artery disorder.