SKP1 and heart disorder: Regarding the miRNA–mRNA pairs, miR-125a-5p/NIPAL4, miR-135a-5p/ZNF385B, miR-140-3p/FKBP3, miR-140-3p/SKP1 and miR-140-3p/NDUFA4, very little or nothing is known about the function of these genes in cardiac disease.