TP53 and cancer: Mutations in the TP53 often lead to (1) disrupted cell cycle control—mutated p53 fails to stop damaged cells from dividing uncontrollably; (2) increased invasiveness and metastasis—mutations can activate pathways that enhance cell migration and invasiveness, promoting metastasis; and (3) interactions with other proteins—mutant p53 can bind to proteins like p63 and p73, altering their functions and increasing the invasive and metastatic capabilities of cancer cells [6,7,8,9].