-Butyrate suppresses inflammatory cytokine production (IL-6, TNF-α, and IL-1β) in peripheral blood mononuclear cells (PBMCs) isolated from patients with mucocutaneous involvement of BD and healthy controls-mRNA levels of the lipopolysaccharide-induced free fatty acid receptor 2 in the PBMCs were higher of BD patients than in healthy controls. The gene discussed is TNF; the disease is Behcet disease.