NFKB1 and neoplasm: The 8305C cells created a considerable tumor mass in 20 days from the implant, showing histopathological characteristics of high-grade neoplasia (high proliferative activity and invasiveness), allowing the evaluation of the effect of Trox in counteracting tumor progression, thus confirming the ability of Trox to modulate the activation of the NF-κB/IκB-α pathway.