Additionally, studies encompassing various pancreatic cancer cell lines (CFPAC-1, BxPC-3, PANC-1, SW1990) and 115 patient tissues demonstrated that decreased expression of miRNA-382 correlates with increased levels of ANXA3 (Annexin A3), an activator of the PI3K/AKT pathway. Here, ANXA3 is linked to familial pancreatic carcinoma.