ESR1 and Infertility: Although, the genetic background of endometriosis-associated infertility was extensively studied and several SNVs were identified within or close to genes involved in the regulation of estrogen signaling (CYP19 [39], ESR1 [24]), steroid hormone production ((LHR, LH) [40]) and inflammation ((MUC2) [41]), we report for the first time that rs2046210 is associated with this condition.