TRMT10C and diabetes mellitus: Furthermore, we also showed that overexpression of Sod2 protects against diabetes-induced decreases in MRPP1 and its interactions with LncCytB; Sod2-overexpressing diabetic mice are also protected from decreases in retinal LncCytB and mtDNA nucleoids and increases in ROS and do not develop retinopathy [13,26], supporting the role of MRPP1–LncCytB in diabetic retinopathy.