Resveratrol can upregulate the expression of proapoptotic genes BAX, BID, and BAK and downregulate the antiapoptotic ones, MCL-1, BCL-2, and BCL-XL, in several human and rodent PCa cell lines, namely, LNCaP, C4-2B, DU145, PC3, as well as TRAMP-C1, TRAMP-C2, and TRAMP-C3 [633,638,639,640,641]. Here, BCL2 is linked to posterior cortical atrophy.