Stimulation of PCa cells with apigenin strongly induced the expression of DR5 and TNF-related apoptosis-inducing ligand (TRAIL) death receptors [332,333] as well as caspase-8, caspase-10, caspase-9, and caspase-3 [317,330,331,332]. This evidence concerns the gene CASP9 and posterior cortical atrophy.