Specifically, lncRNAs, such as LINC00858 in colon cancer, LOC100996425 in prostate cancer and LINC00511 in colorectal cancer, were shown to induce tumorigenesis and cancer progression via regulation of HNF4α and associated signaling pathways such as AMPK/mTOR [165,166,167]. Here, HNF4A is linked to colorectal cancer.