Examples of Ovs associated with CAR-T cells are given by Ovs expressing IL-15/il-15Rα, potentiating the antitumor effect of EGFR-CAR-NK cells in GBM mouse models [18], or Ovs expressing IL-7, improving the efficacy of B7H3-CAR-T cells for glioblastoma therapy [19]. This evidence concerns the gene IL15 and glioblastoma.