In the iCCA context, three classifications were proposed between 2012 and 2013: Andersen et al. proposed a classification based on transcriptomic profiles and mutations in KRAS, EGFR, and BRAF genes [198]; Oishi et al. grouped iCCA tumors according to mRNA and miRNA expression [199]; and Sia et al. proposed a categorization based on gene expression profiles and activation of specific signaling pathways [95]. Here, KRAS is linked to infantile convulsions and choreoathetosis.