Immune-related marker profiling showed that the tumor-associated macrophages that were CD14-positive expressed both pro-inflammatory, i.e., immunoactivating, IFNγ, TNFα, IL-1β, IL-12, and anti-inflammatory, i.e., immunosuppressive, IL-4 and IL-10 cytokines colocalized in the same cells on the ex vivo cell preparations obtained from all tumor samples examined (Figure 6 and Figure S3). Here, TNF is linked to neoplasm.