CD163 and breast cancer: Although a high density of CD163+ tumour-associated macrophages (TAMs) in BC is associated with poor survival outcomes [46], Mansfield et al. (2012) found that in BC SLNs, the presence of sinusoidal CD163+ macrophages was associated with favourable nodal status, suggesting that the impact of CD163+ macrophages may depend on the microenvironment [11].