The G ≥3 rate was 42%, and the most common G ≥3 AEs were hypertension (14.1%), ALT increase (11.6%), AST increase (6.6%), diarrhea (3%), skin rash (1.1%), edema, constipation, and fatigue (0.8% each), nausea/vomiting (0.6% each), and abdominal pain (0.3%). The gene discussed is GPT; the disease is hypertensive disorder.