In the context of FGFR, a study involving 115 patients with CCA showed that mutations in FGFR2 were the most frequent at 6.1%, in contrast to FGFR1 mutations at 0.9% and no mutations in FGFR3–5 [72,73,74]. The gene discussed is FGFR2; the disease is cholangiocarcinoma.