Mutations in SNRNP200 have been linked to conditions like autosomal dominant retinitis pigmentosa and single-cell RNA-seq studies in acute myeloid leukemia (AML) cells have demonstrated a strong association between cell surface expression of U5 snRNP200 and components of the antiviral innate response pathway [43,44]. The gene discussed is SNRNP200; the disease is acute myeloid leukemia.