In nasopharyngeal carcinoma, sorcin silencing results in the expression of the multidrug-resistance genes MDR1 (ABCB1), MRP1, and ERCC1, the detoxification enzyme GST-π, the Rho GTPase RhoE, and the anti-apoptotic proteins Bcl-2 and Survivin. Here, ABCB1 is linked to nasopharyngeal carcinoma.