Sorcin transfection in several tumor cell lines (leukemia, lung, gastric, ovarian, and breast cancers) increases resistance to common chemotherapy drugs, e.g., paclitaxel, doxorubicin, vincristine, etoposide, 5-fluorouracil and homoharringtonine [73,75,80,84,86,94,109,110,111]. Here, SRI is linked to leukemia.