VEGFA and hemangioblastoma: Several anti-angiogenic treatments such as multi-target tyrosine kinase inhibitors (semaxanib, sunitinib, vatalanib, pegaptanib, vandetanib, dovitinib) [116,117,118], thalidomide [119], the VEGF-targeting antibodies ranibizumab and bevacizumab, and interferon alfa-2a have been retrospectively shown to enable disease control in hemangioblastomas but the most promising treatment is belzutifan [116,118].