Moreover, Wang et al. demonstrated that METTL3 or METTL14 deficiency in tumors leads to an increase in cytotoxic tumor-infiltrating CD8+ T cells and an elevation in the secretion of IFN-γ, Cxcl9, and Cxcl10 within the tumor microenvironment in vivo. The gene discussed is CXCL9; the disease is neoplasm.