Promotes tumorigenesis [37,110,117]. Inhibits tumorigenesis in uterine leiomyoma cells with SRCAP complex mutations [118]. H2A.Z knockout mouse embryos die [148].Regulates neurogenesis [97,98], affects learning and memory [175], and mediates the progression of schizophrenia [176]. Cardiac hypertrophy [105] and regulation of cardiac growth [36]. Here, H2AZ1 is linked to schizophrenia.