SIRT1 and osteoporosis: Liu et al. [218] showed that long chain non-coding RNA TRG-AS1 protects against glucocorticoid-induced osteoporosis in a rat model by regulating the miR-802-mediated CAB39/AMPK/SIRT1/NF-κB axis, highlighting the role of a complex regulatory network involving SIRT1 in bone metabolism.