A meta-analysis using nine eligible studies including 576 cases and 632 controls showed that plasma VWF levels were significantly higher in type 2 diabetic patients with ASCVD than in type 2 diabetic patients without ASCVD (MD, 0.61; 95% CI, 0.32 to 0.90; p < 0.00001) [44]. Here, VWF is linked to atherosclerosis.