The meta-analysis of individual patients’ data, performed in observational studies investigating the association between ADAMTS-13 levels and myocardial infarction, showed that low ADAMTS-13 levels were associated with myocardial infarction risk, with an OR of 1.89 (95% CI, 1.15 to 3.12) for values below the 5th percentile versus above, suggesting that low ADAMTS-13 levels are associated with an increased risk of myocardial infarction [48]. This evidence concerns the gene ADAMTS13 and myocardial infarction.