INS and diabetes mellitus: One recent study indicated that Gingerol Enriched Ginger (GEG, 18.7% 6-gingerol, 1.81% 8-gingerol, 2.86% 10-gingerol, 3.09% 6-shogoal, 0.39% 8-shogaol, and 0.41% 10-shogaol) applied as 0.75% wt/wt in the diet for 8 weeks could enhance insulin production, improve intestinal integrity, and counteract mitochondrial dysfunction in high-fat-diet and streptozotocin-induced diabetes in rats [62].