The available information on Tlcd4 reveals that its mRNA levels could be considered a single biomarker or as part of a set of transcripts of certain diseases, such as acute myeloid leukemia [27], hypertrophic obstructive cardiomyopathy [28], coronary heart disease [29], hypertension [30], acute respiratory distress syndrome induced by sepsis [31], or as a marker of the combined IFN-α therapy of viral hepatitis C [32]. The gene discussed is TLCD4; the disease is hypertrophic cardiomyopathy.