Notably, immune effector cells include lymphokine-activated killer cells, cytokine-induced killer (CIK) cells, tumor-infiltrating lymphocytes (TILs), natural killer (NK) cells, γδ T cells, cytotoxic T lymphocytes (CTLs), and chimeric antigen receptor T cells, with the CIK cells being a heterogeneous population of CD3+ CD56+ and CD3+ CD56-cytotoxic T cells that have antitumor activity against multiple tumor targets [19]. The gene discussed is NCAM1; the disease is neoplasm.