PON1 and amyotrophic lateral sclerosis: Different previous works clearly link both variables [53,54,55], and in the case of ALS patients, this relationship could help understand PON1’s role since there is also clear evidence of the relationship between diet and the disease; it is widely accepted that dietary supplements represent a new approach to improve the health of the ALS population [56], and that early and systematic nutritional intervention on the clinical conditions of ALS patients decreases the percentage of mortality that occurs within the first year of diagnosis [57].