In sporadic CRC, a study evaluated the expression of Nrf2 at the RNA and protein levels, and Gfer at the mRNA level, in the intestinal mucosa of patients with colorectal adenomas (the SpCA group) or without proliferative lesions (the control group), in order to determine whether there was an association between the expression of these two genes and the development of colorectal adenomas. This evidence concerns the gene GFER and colorectal adenoma.